推荐杏吧原创

Amarawan Intasiri

Research Assistant Professor

Summary

My research interest focus on drug property evaluation, which involves the study of drug absorption, distribution, metabolism, excretion, and toxicity to identify the best candidates for developing novel successful drugs.

Education

Selected publications

Isoform Selectivities of Novel 4鈥慔ydroxycoumarin Imines as Inhibitors of Myosin II” J. Smith, J. Brawley, K.C. Bordenave, R. Olsen, A. Intasiri, C.R. Cremo, T.W. Bell, Eur. J. Med. Chem. 2023, 247:115008, 1-14.

“Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds” K. Berger, E. Pauwels, G. Parkinson, G. Landberg, T. Le, V.G. Demillo, L.A. Lumangtad, D.E. Jones, M.A. Islam, R. Olsen, T. Kapri, A. Intasiri, K. Vermeire, S. Rhost, T.W. Bell, J. Med. Chem. 2021, 64, 12865−12876.

“Synthesis and Evaluation of 4鈥怘ydroxycoumarin Imines as Inhibitors of Class II Myosins” J. Brawley, E. Etter, D, Heredia, A. Intasiri, K. Nennecker, J. Smith, B.M. Welcome, R.K. Brizendine, T.W. Gould, T.W. Bell, C. Cremo, J. Med. Chem. 2020, 63, 11131-11148.

“Syntheses and Anti-HIV and Human Cluster of Differentiation 4 (CD4) Down-modulating Potencies of Pyridine-fused Cyclotriazadisulfonamide (CADA) Compounds” L.A. Lumangtad, E. Claeys, S. Hamal, A. Intasiri, C. Basrai, E. Yen-Pon, D. Beenfeldt, K. Vermeire, T.W. Bell, Bioorg. Med. Chem. 2020, 115816. DOI: 10.1016/j.bmc.202.115816